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Immunization

Prenatal Serologic Testing Requirements

COVID-19 Vaccination

For expectant mothers, it is essential to stay informed about COVID-19 vaccinations. The CDC provides comprehensive guidelines and resources regarding COVID-19 vaccines, which can be accessed [here](https://www.cdc.gov/vaccines/covid-19/index.html).

TdaP Vaccine

It is recommended that pregnant individuals receive the TdaP vaccine during each pregnancy. This vaccine protects against tetanus, diphtheria, and pertussis (whooping cough) and is crucial for the health of both the mother and the newborn.

RSV Vaccination

Pregnant women should receive a single dose of Pfizer’s RSV vaccine (Abrysvo) between weeks 32 and 36 of pregnancy, especially from September to January. This vaccination helps protect infants from respiratory syncytial virus (RSV), which can lead to severe respiratory illness in young children.

Hepatitis B Considerations in Pregnancy

Hepatitis B Infection Risks

Hepatitis B infection in pregnant women poses a significant risk to infants at birth. If an infant contracts the hepatitis B virus (HBV), they face a 90% risk of developing chronic HBV infection, leading to serious health issues later, including a 25% lifetime risk of premature death from cirrhosis or hepatocellular carcinoma.

Prevention Strategy

To eliminate mother-to-child transmission of HBV, we must prevent infants born to HBsAg-positive women from becoming infected. The Advisory Committee on Immunization Practices (ACIP) recommends:

  1. Post-Exposure Prophylaxis–: All infants born to mothers who test positive for hepatitis B surface antigen (HBsAg) should receive hepatitis B immune globulin (HBIG) and the hepatitis B vaccine within 12 hours of birth.
  2. Vaccination Series: After the initial dose, the infant must complete the hepatitis B vaccine series as recommended.
  1. Post-Vaccination Testing–: Serologic testing should occur at 9-12 months of age to confirm immunity.

This proactive approach is 85%-95% effective in preventing HBV infection in infants.

Influenza Vaccination

Additionally, pregnant individuals are encouraged to receive the seasonal influenza vaccine to protect themselves and their infants from the flu virus.

  • Prenatal Serologic Testing Requirements
  • COVID – https://www.cdc.gov/vaccines/covid-19/index.html
  • TdaP vaccine with each pregnancy, a single dose of Pfizer’s RSV vaccine  (Abrysvo) during weeks 32 through 36 of pregnancy during Septemeber through January. 
  • Hepatitis B infection in a pregnant woman poses a serious risk to her infant at birth.
    Infants who become infected with hepatitis B virus (HBV) have a 90% risk for developing chronic HBV infection and a 25% lifetime risk for dying prematurely from cirrhosis or hepatocellular carcinoma. 
    A key strategy to eliminate mother-to-child transmission of HBV is to prevent infants born to HBsAg-positive women from becoming infected.        The Advisory Committee on Immunization Practices (ACIP) recommends post-exposure prophylaxis with hepatitis B immune globulin (HBIG) and hepatitis B vaccine within 12 hours of birth to all infants born to hepatitis B surface antigen (HBsAg)-positive women followed by completion of the hepatitis B vaccine series and post-vaccination serologic testing at 9-12 months of age. 
  • This approach has been shown to be 85%-95% effective in preventing HBV infection.

  • Flu

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